Figure 3.

Fundus images of the animals at the endpoint of the experiment. The retinotomies created by the vector injection (asterisk) and by the detachment (arrow) are visible in most of the fundus images. Arrowheads are used to identify retinotomies that could not be specifically assigned to the viral or gas injection based on the video of the surgery or the surgical notes. In GFP1, a solid detachment prevented the acquisition of a clear fundus image, and “+” symbols identify two damaged areas of the retina that cannot be attributed to the virus or gas injection. GFP5 and GFP6 suffered complete detachments, and XIAP5 shows a vitreal hemorrhage, which developed at later stages in the experiment, preventing the acquisition of a fundus image.