Table 2.

Plasma concentrations (medians with ranges) for methoxytyramine, normetanephrine and metanephrine across the reference population.

	n	Age, median	Methoxytyramine (nmol/L)	Normetanephrine (nmol/L)	Metanephrine (nmol/L)
All subjects	423	45	0.028 (0.008–0.100)	0.340 (0.129–1.055)	0.151 (0.030–0.449)
Women	238	45	0.027 (0.008–0.078)	0.336 (0.129–0.946)	0.135 (0.030–0.449)
Men	185	46	0.029 (0.009–0.100)*	0.342 (0.156–1.055)	0.176 (0.058–0.405)**
18–29 years	83	25	0.026 (0.008–0.063)	0.281 (0.129–0.580)	0.138 (0.030–0.264)
30–39 years	65	35	0.028 (0.014–0.089)	0.301 (0.129–0.698)	0.139 (0.047–0.334)
40–49 years	116	45	0.028 (0.014–0.078)	0.320 (0.136–0.788)	0.151 (0.059–0.449)
50–59 years	100	54	0.024 (0.008–0.100)	0.368 (0.174–0.873)	0.164 (0.053–0.405)
>60 years	59	63	0.031 (0.014–0.065)	0.383 (0.156–1.055)	0.159 (0.037–0.329)
Normotensive	161	37	0.028 (0.008–0.100)¥	0.288 (0.129–0.788)¥¥	0.141 (0.042–0.449)¥
Hypertensive	262	50	0.029 (0.009–0.088)	0.362 (0.129–1.055)	0.161 (0.030–0.405)

^*Indicates difference (P = 0.0031) between men and women; **indicates difference (P < 0.001) between men and women; ^¥indicates difference (P < 0.05) between normotensive and hypertensive subjects; ^¥¥indicates difference (P < 0.0001) between normotensive and hypertensive subjects.