Table 1.
Immediate bactericidal effects of the modified WHO-formulation II and TPH 5766 as compared to that of the reference hand rub for pre-surgical hand antisepsis according to EN 12791
| Formulation | duration of application (n × 3 ml) |
Mean (n = 20) log10 pre-value |
Mean (n = 20) log10 reduction |
p-value for difference to reference |
|---|---|---|---|---|
| Reference | 3 min | 4.46 ± 0.63 | 2.56 ± 1.10 | |
| WHO II-modified | 3 min | 4.36 ± 0.52 | 2.22 ± 1.15 | 0.176 |
| WHO II-modified | 5 min | 4.45 ± 0.44 | 2.65 ± 1.03 | 0.731 |
| TPH 5766 | 3 min | 4.41 ± 0.64 | 2.53 ± 1.20 | 0.887 |
| TPH 5766 | 5 min | 4.37 ± 0.52 | 2.75 ± 1.25 | 0.513 |
P < 0.1, one-sided (ANOVA, linear contrasts)