Table 2.

Three-hours bactericidal effects of the modified WHO-formulation II and TPH 5766 as compared to that of the reference hand rub for pre-surgical hand antisepsis according to EN 12791

Formulation	duration of application (n × 3 ml)	Mean (n = 20) log10 pre-value	Mean (n = 20) log10 reduction	p-value fordifference to reference
Reference	3 min	4.47 ± 0.55	2.03 ± 0.93
WHO II-modified	3 min	4.30 ± 0.59	1.41 ± 1.32	0.014a
WHO II-modified	5 min	4.51 ± 0.58	1.74 ± 1.15	0.081
TPH 5766	3 min	4.41 ± 0.65	2.08 ± 1.24	0.847
TPH 5766	5 min	4.32 ± 0.65	2.13 ± 1.17	0.651

P < 0.05, two-sided (ANOVA, linear contrasts)

^asignificantly less efficacious than the reference