Table I.
Inhibition rate of survivin siRNA on cancer cell lines.
| Inhibition rate (mean ± standard deviation, %) | |||||
|---|---|---|---|---|---|
| Cell lines | Groups | 24 h | 48 h | 72 h | 96 h |
| MDA-MB-231 | siRNA | 19.2±4.8a | 17.5±1.4a | 16.6±3.7a | 9.9±2.2a |
| si-NC | 9.1±5.1 | 4.1±2.2 | 4.6±1.9 | −1.5±3.7 | |
| SGC-7901 | siRNA | 9.0±0.8 | 15.5±5.6 | 5.3±1.8 | 6.8±4.8a |
| si-NC | 5.2±3.5 | 8.3±5.0 | 1.1±4.1 | 1.1±3.7 | |
| HeLa | siRNA | 7.1±2.2 | 18.6±2.2 | 25.5±4.6a | 46.3±1.8a |
| si-NC | 8.6±3.6 | 18.3±3.4 | 5.8±4.2 | 33.2±4.3 | |
| A549 | siRNA | 4.0±1.0 | 1.4±2.2 | 25.4±2.5a | 29.4±1.2a |
| si-NC | 2.8±2.4 | 2.3±2.1 | 2.9±3.7 | 3.3±3.1 | |
| SK-OV-3 | siRNA | 1.2±2.1 | 2.8±4.0 | −0.9±4.3 | 7.0±0.9a |
| si-NC | −1.7±3.3 | 3.0±3.2 | −2.4±3.8 | 0.4±1.8 | |
| Raji | siRNA | 2.0±0.4 | 3.0±0.02 | 1.7±5.0 | 10.8±4.0a |
| si-NC | 1.4±0.3 | 0.5±0.7 | 0.5±3.1 | 7.4±7.0 | |
| PC-3 | siRNA | 1.2±1.8 | 0.4±1.5 | 4.7±2.1 | 5.5±2.7a |
| si-NC | 0.2±2.5 | 1.0±0.9 | 1.4±1.9 | −0.5±4.1 | |
a
P<0.05 vs. si-NC control group. siRNA, small interfering RNA; si-NC, scrambled negative control siRNA.