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Metastatic pancreatic adenocarcinoma to thyroid. (a) Three-dimensional tumor clusters with prominent mucin vacuoles on fine-needle aspiration (×1000, Pap). (b) Single tumor cells with abundant intracytoplasmic mucin on fine-needle aspiration (×1000, Pap). (c) Core needle biopsy showing metastatic pancreatic adenocarcinoma (×200, H and E) with positive cytokeratin 7 (d), cancer antigen 19-9 (e), and a negative thyroid transcription factor-1 (f) (×200)
