Figure 5.

Effect of triptolide on UVB-enhanced TG production and DGAT activity in DHS. DHS at the third passage were treated with triptolide (28–112 nM) prior to UVB irradiation (0.62 kJ/m²), then maintained for 24 h. (A) TG and (B) DGAT activity was measured in the harvested cells. Data are presented as the mean ± standard deviation of three dishes. *P<0.05 and **P<0.01 vs. untreated controls; ^#P<0.05, ^##P<0.01 and ^###P<0.001 vs. UVB-irradiated cells. DHS, differentiated hamster sebocytes; TG, triacylglycerol; DGAT, diglyceride acyltransferase; UVB, ultraviolet B.