Figure 5.

Reverse transcription-quantitative polymerase chain reaction analysis of pro-inflammatory cytokines in ischemic cortex tissues with β-actin as an internal control. (A) Following MCAO, mRNA expression of TNF-α and IL-6 was upregulated and this effect was reduced by sesamol treatment. Lane 1, Sham; Lane 2, MCAO; Lane 3, MCAO + sesamol. (B) Relative mRNA expression of TNF-α and IL-6. Values are presented as the mean ± standard error of the mean for five rats in each group. *P<0.05 vs. sham group, **P<0.05 vs. MCAO group. MCAO, middle cerebral artery occlusion; TNF-α, tumour necrosis factor-α; IL-6, interleukin-6.