Table 5.
Low (EC10, NOEC) and median (EC50) effect concentrations of PBO for population growth rates across participant labs and generations (F0, F1). Ratios between F0/F1 endpoints are also reported. Values are in μg/L.*, ANOVA analyses were not significant (P > 0.05) so NOEC was the highest tested concentration. <, effects were observed at the lowest tested concentration, thus it was not possible to estimate a proper NOEC.
| Lab | F0 | F1 | F0 | F1 | F0 | F1 | Ratio F0/F1 | ||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| EC10 | EC10 | EC50 | EC50 | NOEC | NOEC | EC10 | EC50 | NOEC | |
| Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | ||||||
| 1 | 192.7 ± 24.9 | 198.5 ± 22.5 | 821 ± 11.3 | 547.7 ± 37.9 | 100 | 100 | 1 | 1.5 | 1 |
| 2 | 329.2 ± 28.3 | 424.3 ± 18.9 | 460.4 ± 10.7 | 200 | 200 | 0.9 | 1 | ||
| 2 | 484.8 ± 22.7 | 200 | 200 | 1 | |||||
| 3 | 321.9 ± 59.1 | 258.6 ± 18 | 494.8 ± 44.1 | 380.2 ± 73.6 | 200 | 200 | 1.2 | 1.3 | 1 |
| 4 | 172.7 ± 16.7 | 225.4 ± 15.8 | 172.6 ± 76.2 | 100 | 100 | 1 | |||
| 5 | 391.5 ± 27.6 | 535.4 ± 47.2 | 400 | 100 | 4 | ||||
| 5 | 346.5 ± 22.9 | 159.5 ± 19 | 492.8 ± 29.3 | 265.7 ± 19.8 | 200 | 50 | 2.2 | 1.9 | 4 |
| 6 | 226.6 ± 25.3 | 285.1 ± 30.6 | 200 | 400* | 0.5 | ||||
| 7 | 85.7 ± 17.4 | 154.3 ± 66.9 | 220.2 ± 30.5 | 199.2 ± 6.9 | 100 | 100 | 0.6 | 1.1 | 1 |
| 8 | 163.3 ± 10.9 | 126.6 ± 19 | 225.36 ± 12.3 | 280.6 ± 31.5 | 100 | 50 | 1.3 | 0.8 | 2 |
| 9 | 173.5 ± 20.2 | 114.4 ± 34.8 | 310.9 ± 18.1 | 326.5 ± 86.9 | 100 | <25 | 1.5 | 1 | 4 |
| 10 | 232.2 ± 29.1 | 239.3 ± 27.5 | 394.3 ± 10.7 | 345.2 ± 20.2 | 200 | 200 | 1 | 1.1 | 1 |
| 11 | 104.6 ± 10.9 | 134.8 ± 17.6 | 307.4 ± 12.5 | 247.8 ± 19.7 | 100 | 100 | 0.8 | 1.2 | 1 |
| 12 | 93.2 ± 17.8 | 142.2 ± 25.9 | 368.6 ± 27 | 254.8 ± 50.8 | 100 | 100 | 0.7 | 1.4 | 1 |