. Author manuscript; available in PMC: 2018 Feb 1.

Published in final edited form as: Invest Radiol. 2017 Feb;52(2):120–127. doi: 10.1097/RLI.0000000000000322

Table 3.

The acquired parameters were tested for significant differences among the healthy and asthma subjects, and also for change with age. Note: Significant differences are displayed in bold font-type.

Comparison	Healthy vs. Asthma		Young. vs. Old

	Young	Old	Healthy	Asthma
*PFTs*
FEV1%	0.014	0.065	0.15	0.36
FVC%	0.069	0.22	0.24	0.36
FEV1/FVC	0.041	0.20	0.14	0.045
FEF25-75%	0.031	0.12	0.36	0.30
RV/TLC	0.014	0.042	0.020	0.018
DLCO mmol CO	0.060	0.16	0.37	0.42
FeNO ppb	0.036	0.10	0.42	0.57
Eos Sputum %	0.80	0.091	0.063	0.45
*HP ¹²⁹Xe MRI*
Average VDP	0.031	0.13	0.05	0.016

FEV1%=forced expiratory volume in 1 second; FVC%=forced vital capacity; FEF=forced mid-expiratory flow rate; FeNO=fractional exhaled nitric oxide; RV/TLC=residual volume/total lung capacity; VDP=ventilation defect percentage