Table 4.

Univariate analysis of survival of non-small cell lung cancer patients treated by surgery

Characteristic	PFS			OS
	P-value	HR	95% CI	P-value	HR	95% CI
Female	0.564	0.876	0.558–1.374	0.439	0.828	0.514–1.335
Age <60 (years)	0.185	1.324	0.874–2.007	0.161	1.370	0.882–2.128
Smoking	0.966	1.009	0.676–1.507	0.817	1.051	0.688–1.605
Histological type
SCC		1.000	Ref.		1.000	Ref.
ADC	0.051	1.565	0.998–2.455	0.061	1.576	0.979–2.536
Others	0.548	1.192	0.671–2.118	0.647	1.153	0.626–2.124
Differential grade
Poor		1.000	Ref.		1.000	Ref.
Middle	0.009*	0.458	0.255–0.822	0.002*	0.396	0.217–0.720
Well	0.067	0.568	0.310–1.041	0.033*	0.512	0.277–0.946
T stage
T1		1.000	Ref.		1.000	Ref.
T2	0.116	1.447	0.913–2.291	0.032	1.739	1.048–2.885
T3	<0.001*	2.594	1.485–4.532	<0.001*	3.561	1.986–6.385
N stage: N0/N1–3	0.027*	1.584	1.052–2.383	0.024*	1.640	1.069–2.518
TNM stage
I		1.000	Ref.		1.000	Ref.
II	0.337	1.258	0.788–2.007	0.112	1.496	0.911–2.456
III	0.003*	2.167	1.297–3.620	<0.001*	2.605	1.527–4.445
Treatment regimens: surgery alone	0.482	0.865	0.578–1.295	0.177	0.743	0.482–1.144
FA score
0		1.000	Ref.		1.000	Ref.
1	0.143	1.147	0.889–2.257	0.046*	1.664	1.009–2.745
2	<0.001*	3.119	1.861–5.229	<0.001*	3.505	2.024–6.069
PNI ≥46.6	0.001*	0.475	0.300–0.751	0.016*	0.544	0.332–0.891

Note:

^*Statistically significant values, P<0.05.

Abbreviations: PFS, progression-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval; Ref., reference; SCC, squamous cell carcinoma; ADC, adenocarcinoma; FA score, plasma fibrinogen and serum albumin levels score; PNI, prognostic nutritional index; TNM, tumor, node, and metastases.