Figure 1.

Charts showing the mean messenger ribonucleic acid (mRNA) expression of the (A) Th1-specific T box (T-bet)/GATA binding protein-3 (GATA₃) and (B) T-bet/forkhead box P3 (FOXP3) ratios using the peripheral blood mononuclear cells of female healthy controls and patients with Hashimoto’s thyroiditis (HT) from Zahedan, Iran (N = 80). The mRNA expression of the T-bet/GATA₃ ratio was lower among the HT patients than the healthy controls; however, this difference was not significant (P = 0.36). In comparison, the mRNA expression of the T-bet/FOXP3 ratio was significantly higher among HT patients than the healthy controls (P <0.02).

T-bet = Th1-specific T box; GATA₃ = GATA binding protein-3; mRNA = messenger ribonucleic acid; HT = Hashimoto’s thyroiditis; FOXP3 = forkhead box P3.