Figure 2.
Charts showing the mean messenger ribonucleic acid (mRNA) expression of the (A) GATA binding protein-3 (GATA3)/forkhead box P3 (FOXP3) and (B) retinoid-related orphan receptor (ROR)-α/FOXP3 ratios using the peripheral blood mononuclear cells of female healthy controls and patients with Hashimoto’s thyroiditis (HT) from Zahedan, Iran (N = 80). The mRNA expression of both the GATA3/FOXP3 and RORα/FOXP3 ratios was significantly higher among HT patients than the healthy controls (P <0.01 each).
GATA3 = GATA binding protein-3; FOXP3 = forkhead box P3; mRNA = messenger ribonucleic acid; HT = Hashimoto’s thyroiditis; RORα = retinoid-related orphan receptor-α.