(A) MEP pathway intermediates, (B) central metabolism related Calvin Benson Bassham (CBB) and tricarboxylic acid (TCA) cycle metabolites, (C) Reducing currencies and (D) amino acids differentially accumulate in the displayed genotypes relative to parent lines. Shading represents log2-fold change for each metabolite (rows) relative to wild type for each genotype (columns), from -2 (darkest) to 2 (lightest). Abbreviations: DXP: Deoxy-xylulose phosphate, MEP: methyl-erythritol phosphate, CDP-ME: diphosphocytidyl-methylerythritol, CDP-MEP: diphosphocytidyl-methylerythritol phosphate, MEcPP: methyl-erythritol cyclodiphosphate, HMBDP: hydroxymethylbutenyl pyrophosphate, DMAPP: dimethylallyl pyrophosphate, RubP: ribulose 1,5 bisphosphate, DHAP: dihydroxyacetone phosphate, NAD: nicotinamide adenine dinucleotide, NADP: nicotinamide adenine dinucleotide phosphate.