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Glucose starvation enhances the cellular response to OPB-51602. (A and B) Proliferation of DU145 and H358 cells treated with OPB-51602 in the presence of 2-DG (A) or 2-FDG (B). (C) STAT3 and pSTAT3 in H358 cells treated with OPB-51602 in FM or glucose-depleted FM (GDM). (D) STAT3 and pSTAT3 in DU145 cells treated with OPB-51602 and/or 2-DG (5 mM) for 4 h in FM.
