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. 2017 Jun 5;114(25):E4924–E4933. doi: 10.1073/pnas.1615730114

Fig. S8.

Fig. S8.

In vivo activity of OPB-51602 in mouse tumor xenografts. (A) Tumor growth assessed in control and OPB-51602 treated animals by in vivo bioluminescence imaging after 2 wk of treatment. (B) Tumor weight assessed in control and OPB-51602 treated animals after 2 wk of treatment. (C and D) Fraction of CD44+/CD24− cells (C) and ex vivo tumor-sphere forming ability (D) in cells isolated from control and OPB-51602 treated tumor xenografts after 2 wk of treatment (40 mg/kg, daily by mouth). *P < 0.01.