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. 2017 Jun 5;114(25):E4996–E5005. doi: 10.1073/pnas.1701201114

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Fig. S1. — dTg-211 mice with reduced forebrain miR-211 levels show higher susceptibility to PTZ-mediated seizures. (A) dTg-211 mice showed higher convulsive scores following PTZ injection, after a Dox administration paradigm. (B) Sequence complementarity of the murine TGFBR2 3′-UTR and the seed sequence of mmu-miR-211-5p, in a conserved 8-mer binding site (TargetScan, P_CT = 0.46). (C) Frontal cortex samples of non–Dox-treated dTg-211 showed reduction of TGFBR2 transcript levels by RT-qPCR. ***P < 0.001.