Fig. S6.

DTg-211 mice do not show elevated anxiety. (A) No difference in time spent in open and closed arms of the elevated plus maze for dTg-211 compared with controls. (B) No difference in the fraction of time spent moving. (C) In the open field test, dTg mice showed no difference in time spent in border of the maze or (D) overall distance moved. (E) Temporal lobe samples from Alzheimer’s disease (AD) patients show hsa-miR-211 levels comparable to those of individuals without AD symptoms (CNT) or nondemented individuals with increased postmortem-observed BRAAK indexes (PATH nonD).