Table S3.
List of GO annotation enrichment analysis using PANTHER
| GO biological process complete | mmu | No. of genes | Expected no. of genes | Overrepresented | Fold enrichment | Enrichment P value |
| Regulation of synaptic vesicle priming (GO:0010807) | 9 | 4 | 0.06 | + | >5 | 0.004 |
| Negative regulation of microtubule polymerization or depolymerization (GO:0031111) | 36 | 5 | 0.25 | + | >5 | 0.0421 |
| Regulation of microtubule polymerization or depolymerization (GO:0031110) | 59 | 6 | 0.4 | + | >5 | 0.0282 |
| Regulation of calcium ion transmembrane transport (GO:1903169) | 61 | 6 | 0.42 | + | > 5 | 0.0341 |
| Regulation of neurotransmitter transport (GO:0051588) | 65 | 6 | 0.44 | + | >5 | 0.0488 |
| Neurotransmitter secretion (GO:0007269) | 88 | 7 | 0.6 | + | >5 | 0.0216 |
| Regulation of synaptic plasticity (GO:0048167) | 136 | 10 | 0.93 | + | >5 | 0.00032 |
| Regulation of exocytosis (GO:0017157) | 165 | 10 | 1.12 | + | >5 | 0.00187 |
| Regulation of ion transmembrane transporter activity (GO:0032412) | 167 | 10 | 1.14 | + | >5 | 0.00208 |
| Regulation of transmembrane transporter activity (GO:0022898) | 172 | 10 | 1.17 | + | >5 | 0.00272 |
| Synaptic transmission (GO:0007268) | 320 | 18 | 2.18 | + | >5 | 8.03E-08 |
| Regulation of transporter activity (GO:0032409) | 182 | 10 | 1.24 | + | >5 | 0.00452 |
| Regulation of synapse structure or activity (GO:0050803) | 237 | 13 | 1.61 | + | >5 | 8.98E-05 |
| Exocytosis (GO:0006887) | 11 | 1.44 | + | >5 | 0.00204 | |
| Modulation of synaptic transmission (GO:0050804) | 289 | 14 | 1.97 | + | >5 | 0.000113 |
| Regulation of protein complex assembly (GO:0043254) | 301 | 14 | 2.05 | + | >5 | 0.000186 |
| Learning or memory (GO:0007611) | 223 | 10 | 1.52 | + | >5 | 0.0272 |
| Cognition (GO:0050890) | 250 | 11 | 1.7 | + | >5 | 0.0105 |
| Regulation of vesicle-mediated transport (GO:0060627) | 396 | 16 | 2.7 | + | >5 | 0.000125 |
| Single-organism behavior (GO:0044708) | 418 | 16 | 2.85 | + | >5 | 0.000262 |
| Cell-cell signaling (GO:0007267) | 537 | 20 | 3.66 | + | >5 | 7.17E-06 |
| Secretion by cell (GO:0032940) | 359 | 13 | 2.44 | + | >5 | 0.00979 |
| Secretion (GO:0046903) | 451 | 16 | 3.07 | + | >5 | 0.00073 |
| Behavior (GO:0007610) | 564 | 20 | 3.84 | + | >5 | 1.64E-05 |
| Positive regulation of secretion (GO:0051047) | 376 | 13 | 2.56 | + | >5 | 0.0162 |
| Regulation of ion transmembrane transport (GO:0034765) | 380 | 13 | 2.59 | + | >5 | 0.0182 |
| Regulation of transmembrane transport (GO:0034762) | 397 | 13 | 2.7 | + | 4.81 | 0.0291 |
| Regulation of neuron projection development (GO:0010975) | 400 | 13 | 2.72 | + | 4.77 | 0.0315 |
| Regulation of cell projection organization (GO:0031344) | 508 | 16 | 3.46 | + | 4.62 | 0.00352 |
| Regulation of cellular component biogenesis (GO:0044087) | 637 | 20 | 4.34 | + | 4.61 | 0.000123 |
| Regulation of ion transport (GO:0043269) | 612 | 19 | 4.17 | + | 4.56 | 0.000344 |
| Regulation of secretion by cell (GO:1903530) | 629 | 17 | 4.28 | + | 3.97 | 0.0122 |
| Regulation of secretion (GO:0051046) | 680 | 18 | 4.63 | + | 3.89 | 0.00789 |
| Neuron development (GO:0048666) | 654 | 17 | 4.45 | + | 3.82 | 0.0204 |
| Cell migration (GO:0016477) | 658 | 17 | 4.48 | + | 3.79 | 0.0221 |
| Cytoskeleton organization (GO:0007010) | 779 | 20 | 5.31 | + | 3.77 | 0.00305 |
| Generation of neurons (GO:0048699) | 1,291 | 33 | 8.79 | + | 3.75 | 3.03E-07 |
| Single-organism cellular localization (GO:1902580) | 669 | 17 | 4.56 | + | 3.73 | 0.0275 |
| Regulation of neurogenesis (GO:0050767) | 683 | 17 | 4.65 | + | 3.65 | 0.0361 |
| Positive regulation of transport (GO:0051050) | 889 | 22 | 6.05 | + | 3.63 | 0.00141 |
| Localization of cell (GO:0051674) | 731 | 18 | 4.98 | + | 3.62 | 0.0216 |
| Cell motility (GO:0048870) | 731 | 18 | 4.98 | + | 3.62 | 0.0216 |
| Locomotion (GO:0040011) | 940 | 23 | 6.4 | + | 3.59 | 0.000882 |
| Neuron differentiation (GO:0030182) | 821 | 20 | 5.59 | + | 3.58 | 0.00684 |
| Regulation of nervous system development (GO:0051960) | 781 | 19 | 5.32 | + | 3.57 | 0.0134 |
| Neurogenesis (GO:0022008) | 1,372 | 33 | 9.34 | + | 3.53 | 1.45E-06 |
| Regulation of cell development (GO:0060284) | 851 | 20 | 5.8 | + | 3.45 | 0.0118 |
| Regulation of transport (GO:0051049) | 1,676 | 39 | 11.41 | + | 3.42 | 5.74E-08 |
| Nervous system development (GO:0007399) | 1,800 | 41 | 12.26 | + | 3.34 | 2.8E-08 |
| Negative regulation of multicellular organismal process (GO:0051241) | 977 | 21 | 6.65 | + | 3.16 | 0.0255 |
| Movement of cell or subcellular component (GO:0006928) | 1,029 | 22 | 7.01 | + | 3.14 | 0.0158 |
| Regulation of cellular localization (GO:0060341) | 1,153 | 24 | 7.85 | + | 3.06 | 0.00823 |
| Regulation of cellular component organization (GO:0051128) | 2,095 | 41 | 14.27 | + | 2.87 | 2.99E-06 |
| Regulation of localization (GO:0032879) | 2,246 | 43 | 15.3 | + | 2.81 | 1.92E-06 |
| Positive regulation of signaling (GO:0023056) | 1,326 | 25 | 9.03 | + | 2.77 | 0.0277 |
| Positive regulation of cell communication (GO:0010647) | 1,446 | 27 | 9.85 | + | 2.74 | 0.0128 |
| Regulation of biological quality (GO:0065008) | 2,643 | 47 | 18 | + | 2.61 | 2.47E-06 |
| Regulation of signaling (GO:0023051) | 2,486 | 42 | 16.93 | + | 2.48 | 0.000135 |
| Regulation of cell communication (GO:0010646) | 2,620 | 44 | 17.84 | + | 2.47 | 6.48E-05 |
| Single-organism localization (GO:1902578) | 2,664 | 44 | 18.14 | + | 2.43 | 0.000107 |
| Regulation of molecular function (GO:0065009) | 2,260 | 35 | 15.39 | + | 2.27 | 0.0215 |
| Single-organism transport (GO:0044765) | 2,467 | 38 | 16.8 | + | 2.26 | 0.00811 |
| Localization (GO:0051179) | 4,100 | 59 | 27.92 | + | 2.11 | 2.24E-05 |
| System development (GO:0048731) | 3,499 | 49 | 23.83 | + | 2.06 | 0.00226 |
| Establishment of localization (GO:0051234) | 3,295 | 45 | 22.44 | + | 2.01 | 0.017 |
| Positive regulation of biological process (GO:0048518) | 4,910 | 67 | 33.44 | + | 2 | 8.53E-06 |
| Transport (GO:0006810) | 3,170 | 43 | 21.59 | + | 1.99 | 0.0372 |
| Negative regulation of cellular process (GO:0048523) | 3,811 | 49 | 25.95 | + | 1.89 | 0.0283 |
| Positive regulation of cellular process (GO:0048522) | 4,363 | 56 | 29.71 | + | 1.88 | 0.00394 |
| Cellular component organization or biogenesis (GO:0071840) | 4,260 | 54 | 29.01 | + | 1.86 | 0.0106 |
| Anatomical structure development (GO:0048856) | 4,183 | 53 | 28.49 | + | 1.86 | 0.0143 |
| Multicellular organismal development (GO:0007275) | 4,036 | 51 | 27.49 | + | 1.86 | 0.027 |
| Cellular component organization (GO:0016043) | 4,121 | 51 | 28.06 | + | 1.82 | 0.0497 |
| Regulation of cellular process (GO:0050794) | 9,809 | 102 | 66.8 | + | 1.53 | 5.42E-05 |
| Biological regulation (GO:0065007) | 10,699 | 109 | 72.86 | + | 1.5 | 1.74E-05 |
| Regulation of biological process (GO:0050789) | 10,256 | 103 | 69.84 | + | 1.47 | 0.000353 |
| Cellular process (GO:0009987) | 13,249 | 122 | 90.23 | + | 1.35 | 0.000246 |
| Single-organism process (GO:0044699) | 12,188 | 111 | 83 | + | 1.34 | 0.0171 |
| Unclassified (UNCLASSIFIED) | 1,652 | 8 | 11.25 | − | 0.71 | 0 |