N-glycoproteomic profiles classify lymphomas according to lineage, cell of origin, and WHO subtype. (A) Thirty-two cell lines included in this study are accurately classified according to their lineage (B or T/NK cells), cell of origin (pre-GC– and GC-derived B cells), and WHO subtypes. (B) Clustering of eight blinded primary B-cell lymphoma samples based on their Pearson’s correlations with the 32 cell lines accurately designated the profiles of clinical samples P1 to P4, which are highly correlated to MCL cell lines, whereas clinical samples P5 to P8 are highly correlated to t-FL cell lines. NLPHL, nodular lymphocyte predominant Hodgkin lymphoma; MF, mycosis fungoides; SS, Sézary syndrome; T-ALL, T-lymphoblastic leukemia/lymphoma.