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. Author manuscript; available in PMC: 2018 Apr 29.
Published in final edited form as: Biochem Biophys Res Commun. 2017 Mar 12;486(2):307–313. doi: 10.1016/j.bbrc.2017.03.033

Fig. 4. KU60648 enhances DNA damage when combined with IR in human OS cells.

Fig. 4

Representative confocal microscopy images of γH2AX foci 24 hours post-IR in cells treated with vehicle control, 5 Gy or 5 Gy plus 100 nM KU60648 (added 1 hour before IR) in 143B cells (A) and U2OS cells (B). Quantification of percentage of cells with > 20 γH2AX foci in cells treated with vehicle control, 100 nM KU60648 alone, 5 Gy or 5 Gy plus 100 nM KU60648 in 143B cells (C) and U2OS cells (D). Results are mean ± SD from 2 independent experiments. For each treatment group, >150 and >90 nuclei were counted for 143B and U2OS cells, respectively.