Table 1.
Demographic, clinical and laboratory characteristics for 11,836 long-term hemodialysis patients who received kidney transplants. Data are from the last or second to last calendar quarter prior to transplantation. Values are in percentage or mean ± SD or median (IQR), as appropriate
| Variables | All | With DGF | Without DGF | p-value |
|---|---|---|---|---|
| N (%) | 11,836 (100) | 2,628 (22.2) | 9,208 (77.8) | N/A |
| Age (years) | 49±14 | 50±13 | 48±14 | <0.001 |
| Gender (% women) | 38 | 34 | 39 | <0.001 |
| Diabetes mellitus (%) | 26 | 29 | 26 | <0.001 |
| Race/Ethnicity (%) | ||||
| Whites | 46 | 39 | 48 | <0.001 |
| African Americans | 27 | 35 | 25 | <0.001 |
| Hispanics | 14 | 14 | 14 | 0.85 |
| Asians | 4 | 3 | 4 | 0.01 |
| Dialysis vintage time (%): | ||||
| <6 months | 12 | 6 | 14 | <0.001 |
| 6-24 months | 28 | 19 | 31 | <0.001 |
| 2-5 years | 36 | 41 | 35 | <0.001 |
| >5 years | 24 | 34 | 21 | <0.001 |
| Primary insurance (%) | ||||
| Medicare | 52 | 59 | 50 | <0.001 |
| Medicaid | 3 | 3 | 3 | 0.47 |
| Private Insurance | 16 | 14 | 17 | 0.003 |
| Other | 20 | 14 | 22 | <0.001 |
| Marital Status (%) | ||||
| Married | 47 | 46 | 48 | 0.26 |
| Divorced | 6 | 6 | 6 | 0.65 |
| Single | 27 | 28 | 27 | 0.17 |
| Widowed | 3 | 3 | 3 | 0.98 |
| BMI (kg/m2) | 26.8±6.0 | 28.0±6.7 | 26.4±5.7 | <0.001 |
| Kt/V (dialysis dose) | 1.61±0.35 | 1.60±0.33 | 1.62±0.36 | 0.055 |
| nPCR (g/kg/day) | 1.05±0.25 | 1.06±0.25 | 1.05±0.26 | 0.01 |
| Serum albumin (g/dL) | 4.02±0.37 | 4.00±0.37 | 4.03±0.38 | <0.001 |
| creatinine (mg/dL) | 10.6±3.2 | 11.1±3.1 | 10.5±3.2 | <0.001 |
| bicarbonate (mg/dL) | 21.9±3.4 | 22.2±3.3 | 21.8±3.4 | <0.001 |
| TIBC (mg/dL) | 212±40 | 208±39 | 213±41 | <0.001 |
| ferritin (ng/mL) * | 469 (249-731) | 534 (299-786) | 448 (236-717) | <0.001 |
| phosphorus (mg/dL) | 5.95±1.54 | 5.97±1.57 | 5.94±1.53 | 0.41 |
| calcium (mg/dL) | 9.43±0.74 | 9.42±0.77 | 9.44±0.73 | 0.23 |
| Blood hemoglobin (g/dL) | 12.3±1.2 | 12.2±1.3 | 12.3±1.2 | 0.001 |
| WBC (×103/l) | 6.8±2.0 | 6.9±2.1 | 6.8±2.1 | 0.24 |
| Lymphocyte (%total WBC) | 23±8 | 23±8 | 23±8 | 0.22 |
| Pre-transplant transfusion (%) | 31 | 36 | 30 | <0.001 |
| Number of HLA mismatch * | 4 (3-5) | 4 (2-5) | 4 (3-5) | <0.001 |
| PRA (%) * | 0 (0-3) | 0 (0-4) | 0 (0-3) | 0.21 |
| Cold Ischemia time (hours) * | 14 (4-22) | 19 (12-25) | 12 (2-20) | <0.001 |
| EDC kidney (%) | 19 | 23 | 17 | <0.001 |
| Donor type (% Living) | 32 | 10 | 38 | <0.001 |
| Donor age (years) | 39±15 | 42±15 | 38±15 | <0.001 |
BMI: body mass index, EDC: Extended Donor Criteria, HLA: human leukocyte antigen, TIBC: total iron binding capacity; nPNA: normalized protein nitrogen appearance, PRA: panel reactive antibody (last value prior to transplant), WBC: white blood cell.
*
median (IQR)