Table 1. Demographic and clinical details of subjects participating to the study.
Healthy controls (N = 35) | Patients with Bipolar Disorder (N = 33,18 BD I, 15 BD II) | Patients with Schizophrenia (N = 19) | ||
---|---|---|---|---|
Mean (SD) | Mean (SD) | Mean (SD) | ||
Age (years, mean(SD)) | 39.0 (12.6) | 48.9 (8.3) | 46.1 (11.5) | |
Sex (males/females)* | 19/16 | 8/25 | 13/6 | |
Duration of Illness (years, mean(SD)) | - | 20.8 (10.5) | 20.8 (12.6) | |
BPRS total score (mean(SD)) | - | 33.0 (8.3) | 34.3 (6.7) | |
HDRS total score (mean(SD)) | - | 11.5 (11.8) | - | |
BRMRS total score (mean(SD)) | - | 3.1 (4.4) | - | |
Psychotic symptoms (yes/no) | - | 20/13 | 19/0 | |
Number of hospitalizations (mean(SD)) | - | 5.3 (4.8) | 4.1 (4.9) | |
Medication | AP typical (chlorpromazine equivalents, yes/no, mean(SD)* | - | 15/18 99.2 (104.1) | 7/12 68.4 (41.6) |
AP atypical (chlorpromazine equivalents, yes/no, mean(SD)* | - | 7/26 255.0 (142.0) | 12/7 280.6 (123.8) | |
AD (PDD/DDD, yes/no, mean(SD)) | - | 13/20 1.64 (0.63) | 9/10 1.16 (0.65) | |
BZD (PDD/DDD, yes/no, mean(SD)* | - | 12/21 2.42 (3.84) | 9/10 3.83 (4.87) | |
STAB (PDD/DDD, yes/no, mean(SD)* | - | 11/22 0.91 (0.24) | 0/19 |
Demographic and clinical details of our sample. BD = bipolar disorder; SD = standard deviation; BPRS = Brief Psychiatric Rating Scale; HDRS = Hamilton Depression Rating Scale; BRMRS = Bech-Rafaelsen Mania Rating Scale; AP = Antipsychotics; AD = Antidepressants; BZD = benzodiazepines; STAB = Mood stabilizers.
*gender significantly different between samples (Chi-squared test, p < 0.05).