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. 2017 Jun 28;12(6):e0178089. doi: 10.1371/journal.pone.0178089

Table 1. Demographic and clinical details of subjects participating to the study.

Healthy controls (N = 35) Patients with Bipolar Disorder (N = 33,18 BD I, 15 BD II) Patients with Schizophrenia (N = 19)
Mean (SD) Mean (SD) Mean (SD)
Age (years, mean(SD)) 39.0 (12.6) 48.9 (8.3) 46.1 (11.5)
Sex (males/females)* 19/16 8/25 13/6
Duration of Illness (years, mean(SD)) - 20.8 (10.5) 20.8 (12.6)
BPRS total score (mean(SD)) - 33.0 (8.3) 34.3 (6.7)
HDRS total score (mean(SD)) - 11.5 (11.8) -
BRMRS total score (mean(SD)) - 3.1 (4.4) -
Psychotic symptoms (yes/no) - 20/13 19/0
Number of hospitalizations (mean(SD)) - 5.3 (4.8) 4.1 (4.9)
Medication AP typical (chlorpromazine equivalents, yes/no, mean(SD)* - 15/18 99.2 (104.1) 7/12 68.4 (41.6)
AP atypical (chlorpromazine equivalents, yes/no, mean(SD)* - 7/26 255.0 (142.0) 12/7 280.6 (123.8)
AD (PDD/DDD, yes/no, mean(SD)) - 13/20 1.64 (0.63) 9/10 1.16 (0.65)
BZD (PDD/DDD, yes/no, mean(SD)* - 12/21 2.42 (3.84) 9/10 3.83 (4.87)
STAB (PDD/DDD, yes/no, mean(SD)* - 11/22 0.91 (0.24) 0/19

Demographic and clinical details of our sample. BD = bipolar disorder; SD = standard deviation; BPRS = Brief Psychiatric Rating Scale; HDRS = Hamilton Depression Rating Scale; BRMRS = Bech-Rafaelsen Mania Rating Scale; AP = Antipsychotics; AD = Antidepressants; BZD = benzodiazepines; STAB = Mood stabilizers.

*gender significantly different between samples (Chi-squared test, p < 0.05).