Table 2. Brain areas where diffusion indexes are different in schizophrenia patients in respect to healthy controls.
FA | |||
Tract | SCZ patients | Healthy controls | rank-sum (p) |
mean (SD) x10 2 | mean (SD) x10 2 | ||
Corpus callosum | 0.70 (0.12) | 0.73 (0.12) | <10−3 |
Corona radiata L | 0.51 (0.10) | 0.53 (0.099) | <10−3 |
Corona radiata R | 0.51 (0.098) | 0.53 (0.095) | <10−3 |
Longitudinal fasciculus L | 0.51 (0.097) | 0.53 (0.099) | <10−3 |
Longitudinal fasciculus R | 0.51 (0.095) | 0.53 (0.099) | <10−3 |
External capsule L | 0.46 (0.11) | 0.48 (0.11) | <10−3 |
External capsule R | 0.47 (0.11) | 0.48 (0.11 | <10−3 |
Thalamic radiation L | 0.62 (0.10) | 0.65 (0.11) | <10−3 |
Thalamic radiation R | 0.62 (0.10 | 0.65 (0.11) | <10−3 |
MD | |||
Tract | SCZ patients | Healthy controls | rank-sum (p) |
mean (SD) x10 4 | mean (SD) x10 4 | ||
Corpus callosum | 8.17 (2.23) | 7.63 (1.26) | <10−3 |
Corona radiata L | 7.40 (0.94) | 7.18 (0.85) | <10−3 |
Corona radiata R | 7.43 (0.50) | 7.17 (0.83) | <10−3 |
Internal capsule L | 7.31 (0.81) | 7.19 (0.77) | <10−3 |
Internal capsule R | 7.37 (1.07) | 7.22 (0.79) | <10−3 |
Longitudinal fasciculus L | 7.25 (0.80) | 7.02 (0.76) | <10−3 |
Longitudinal fasciculus R | 7.29 (0.84) | 7.05 (0.80) | <10−3 |
External capsule L | 7.82 (0.83) | 7.63 (0.76) | <10−3 |
External capsule R | 7.77 (0.84) | 7.64 (0.75) | <10−3 |
Thalamic radiation L | 8.23 (.1.41) | 7.72 (1.42) | <10−3 |
Thalamic radiation R | 8.22 (2.69( | 7.60 (1.30) | <10−3 |
VR | |||
Tract | SCZ patients | Healthy controls | rank-sum (p) |
mean (SD) | mean (SD) | ||
Corpus callosum | 0.44 (0.19) | 0.41 (0.19) | <10−3 |
Longitudinal fasciculus R L | 0.70 (0.11) | 0.67 (0.12) | <10−3 |
External capsule L | 0.76 (0.12) | 0.74 (0.12) | <10−3 |
External capsule R | 0.75 (0.12) | 0.74 (0.12) | <10−3 |
AD | |||
Tract | SCZ patients | Healthy controls | rank-sum (p) |
mean (SD) x10 3 | mean (SD) | ||
Corpus callosum | 1.74 (0.48) | 1.69 (0.45) | <10−3 |
Internal capsula R | 1.35 (0.15) | 1.34 (0.15) | <10−3 |
Corona radiata L | 1.26 (0.21) | 1.23 (0.17) | <10−3 |
Corona radiata R | 1.27 (0.21) | 1.23 (0.18) | <10−3 |
RD | |||
Tract | SCZ patients | Healthy controls | rank-sum (p) |
mean (SD) x10 4 | mean (SD) x10 4 | ||
Corpus callosum | 3.96 (1.57) | 3.57 (1.47) | <10−3 |
Corona radiata L | 5.16 (1.03) | 4.85 (0.95) | <10−3 |
Corona radiata R | 5.15 (0.97) | 4.83 (0.91) | <10−3 |
Internal capsule L | 4.25 (0.94) | 4.11 (0.93) | <10−3 |
Internal capsule R | 4.24 (0.97) | 4.12 (0.95) | <10−3 |
Longitudinal fasciculus L | 5.03 (0.84) | 4.76 (0.81) | <10−3 |
Longitudinal fasciculus R | 5.05 (0.84) | 4.79 (0.84) | <10−3 |
External capsule L | 5.70 (1.06) | 5.45 (1.02) | <10−3 |
External capsule R | 5.65 (1.07) | 5.45 (1.01) | <10−3 |
Thalamic radiation L | 4.91 (1.35) | 4.42 (1.44) | <10−3 |
Thalamic radiation R | 4.59 (1.32) | 4.24 (1.32) | <10−3 |
Brain areas where diffusion indexes are statistically different between patients affected by schizophrenia and healthy controls, mean and standard deviations of their values (FA = fractional anisotropy, MD = mean diffusivity, VR volume ratio, RD = radial diffusivity, L = left, R = right, SD = standard deviation) and results of the Wilcoxon rank-sum test.