Table 3. Brain areas where diffusion indexes are different in bipolar disorder patients in respect to healthy controls.
| FA | |||
| Tract | BD patients | Healthy controls | rank-sum (p) |
| mean (SD) x10 2 | mean (SD) x10 2 | ||
| Corpus callosum | 0.69 (0.13) | 0.73 (0.12) | <10−3 |
| Corona radiata L | 0.49 (0.097) | 0.53 (0.099) | <10−3 |
| Corona radiata R | 0.50 (0.098) | 0.53 (0.095) | <10−3 |
| Internal capsule L | 0.63 (0.095) | 0.65 (0.094) | <10−3 |
| Internal capsule R | 0.63 (0.093) | 0.65 (0.095) | <10−3 |
| Longitudinal fasciculus L | 0.51 (0.098) | 0.53 (0.099) | <10−3 |
| Longitudinal fasciculus R | 0.51 (0.099) | 0.53 (0.099) | <10−3 |
| MD | |||
| Tract | BD patients | Healthy controls | rank-sum (p) |
| mean (SD) x10 4 | mean (SD) x10 4 | ||
| Corpus callosum | 8.13 (1.51) | 7.63 (1.26) | <10−3 |
| Corona radiata L | 7.50 (0.93) | 7.18 (0.85) | <10−3 |
| Corona radiata R | 7.49 (0.92) | 7.17 (0.83) | <10−3 |
| Internal capsule L | 7.39 (0.85) | 7.19 (0.77) | <10−3 |
| Internal capsule R | 7.43 (0.83) | 7.22 (0.79) | <10−3 |
| Longitudinal fasciculus L | 7.24 (0.76) | 7.02 (0.76) | <10−3 |
| Longitudinal fasciculus R | 7.29 (0.78) | 7.05 (0.80) | <10−3 |
| External capsule L | 7.84 (0.81) | 7.63 (0.76) | <10−3 |
| External capsule R | 7.74 (0.79) | 7.64 (0.75) | <10−3 |
| Thalamic radiation L | 8.18 (.1.37) | 7.72 (1.42) | <10−3 |
| Thalamic radiation R | 8.21 (2.57) | 7.60 (1.30) | <10−3 |
| VR | |||
| Tract | BD patients | Healthy controls | rank-sum (p) |
| mean (SD) | mean (SD) | ||
| Corpus callosum | 0.47 (0.20) | 0.41 (0.19) | <10−3 |
| Corona radiata L | 0.73 (0.11) | 0.68 (0.12) 68 |
<10−3 |
| Corona radiata R | 0.72 (0.11) | 0.68 (0.12) | <10−3 |
| Longitudinal fasciculus R L | 0.70 (0.12) | 0.68 (0.12) | <10−3 |
| External capsule L | 0.77 (0.12) | 0.74 (0.12) | <10−3 |
| External capsule R | 0.76 (0.12) | 0.73 (0.12) | <10−3 |
| Cingulum L | 0.65 (0.13) | 0.59 (0.15) | <10−3 |
| AD | |||
| Tract | BD patients | Healthy controls | rank-sum (p) |
| mean (SD) x10 3 | mean (SD) x10 3 | ||
| Corona radiata R | 1.20 (0.16) | 1.19 (0.15) | <10−3 |
| Longitudinal fasciculus R | 1.18 (0.17) | 1.16 (0.18) | <10−3 |
| Internal capsule R | 1.35 (0.16) | 1.34 (0.15) | <10−3 |
| RD | |||
| Tract | BD patients | Healthy controls | rank-sum (p) |
| mean (SD) x10 4 | mean (SD) x10 4 | ||
| Corpus callosum | 4.21 (1.73) | 3.57 (1.47) | <10−3 |
| Corona radiata L | 5.30 (1.01) | 4.85 (0.95) | <10−3 |
| Corona radiata R | 5.25 (1.00) | 4.83 (0.91) | <10−3 |
| Internal capsule L | 4.35 (0.99) | 4.11 (0.93) | <10−3 |
| Internal capsule R | 4.38 (0.97) | 4.13 (0.95) | <10−3 |
| Longitudinal fasciculus L | 5.05 (0.84) | 4.76 (0.81) | <10−3 |
| Longitudinal fasciculus R | 5.05 (0.87) | 4.79 (0.84) | <10−3 |
| MO | |||
| Tract | BD patients | Healthy controls | rank-sum (p) |
| mean (SD) | mean (SD) | ||
| Corpus callosum | 0.86 (0.18) | 0.88 (0.16) | <10−3 |
Brain areas where diffusion indexes are statistically different between patients affected by bipolar disorder and healthy controls, mean and standard deviations of their values ((FA = fractional anisotropy, MD = mean diffusivity, VR volume ratio, RD = radial diffusivity, MO = mode, L = left, R = right, SD = standard deviation) and results of the Wilcoxon rank-sum test.