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Grey dots along Hsa5 represent genes whose paralogs are plotted directly above or below the dot on the human chromosomes on which they occur. Note that chromosomes 1, 15, and 19 share many paralogs with the TNFAIP8-containing region of Hsa5. This result suggests that these four genes originated as ohnologs in rounds 1 and 2 of the vertebrate genome duplication events (VGD1 and VGD2).
