Table 4. Reaction showing the largest flux increase after CINADH inhibition.

Absolute flux shift mmol gcel−1 h−1	Reaction name	Reaction formula	Related metabolism
0,5841	Succinate Dehydrogenase (Ubiquinone) Mitochondrial	q6[m] + succ[m] ↔ q6h2[m] + fum[m]	Citrate cycle (TCA cycle)
0,5315	glycerol-3-phosphate dehydrogenase (NAD)	h[c] + nadh[c] + dhap[c] → nad[c] + glyc3p[c]	Glycerolipid Metabolism
0,3562	isocitrate dehydrogenase (NADP+) Mitochondrial	icit[m] + nadp[m] → co2[m] + akg[m] + nadph[m]	Citrate cycle (TCA cycle)
0,0857	Pyruvate dehydrogenase mitochondrial	coa[m] + pyr[m] + nad[m] → co2[m] + accoa[m] + nadh[m]	Glycolysis/ Gluconeogenesis
0,0837	Valine reversible mitochondrial transport via proton symport	h[c] + val-L[c] ↔ h[m] + val-L[m]	Transport Mitochondrial
0,0837	Valine transaminase mitochondrial	akg[m] + val-L[m] ↔ 3mob[m] + glu-L[m]	Valine, leucine and isoleucine Metabolism
0,083	Valine transaminase	akg[c] + val-L[c] ↔ 3mob[c] + glu-L[c]	Valine, leucine and isoleucine Metabolism
0,0577	Succinate-CoA ligase (ATP-forming), mitochondrial	atp[m] + coa[m] + succ[m] ↔ adp[m] + pi[m] + succoa[m]	Citrate cycle (TCA cycle)
0,0577	2-Oxoglutarate Dehydrogenase (Mitochondrial)	coa[m] + akg[m] + nad[m] → co2[m] + succoa[m] + nadh[m]	Citrate cycle (TCA cycle)
0,0494	Phosphoglycerate mutase	2pg[c] ↔ 3pg[c]	Glycolysis/ Gluconeogenesis