Table 5. Comparison of Levene's test Pv ranks from different centiles of the Pm rank-ordered distribution for the index traits.
Trait | Known SNPs | Min Pm from 100th centile | Max Pm from 100th centile | Median Pv rank for 100th centile | Median Pv rank for 99th-1st centiles | Mann-Whitney P-value | Min Pm from 99th centile | Max Pm from 99th centile | Median Pv rank for 99th centile | Median Pv rank for 98th-1st centiles | Mann-Whitney P-value |
---|---|---|---|---|---|---|---|---|---|---|---|
BMI | Included | 4.78×10−91 | 5.82×10−3 | 58.82 | 49.93 | 1.46×10−5 | 5.86×10−3 | 1.85×10−2 | 52.79 | 49.91 | 0.42 |
BMI | Excluded | 3.59×10−6 | 8.56×10−3 | 55.78 | 49.95 | 4.30×10−4 | 8.73×10−3 | 2.18×10−2 | 52.60 | 49.93 | 0.36 |
HDL-C | Included | 3.56×10−573 | 6.48×10−3 | 51.49 | 49.99 | 0.47 | 6.48×10−3 | 1.67×10−2 | 50.49 | 49.98 | 0.92 |
HDL-C | Excluded | 6.68×10−11 | 9.94×10−3 | 51.45 | 49.99 | 0.77 | 9.95×10−3 | 2.09×10−2 | 51.06 | 49.98 | 0.47 |
LDL-C | Included | 3.80×10−143 | 7.14×10−3 | 53.11 | 49.98 | 0.52 | 7.18×10−3 | 1.75×10−2 | 48.44 | 49.99 | 0.85 |
LDL-C | Excluded | 2.03×10−11 | 9.88×10−3 | 53.42 | 49.97 | 0.38 | 9.90×10−3 | 2.09×10−2 | 48.37 | 49.99 | 1.00 |
TG | Included | 2.23×10−113 | 8.18×10−3 | 53.73 | 49.98 | 0.32 | 8.19×10−3 | 1.92×10−2 | 52.42 | 49.95 | 0.63 |
TG | Excluded | 1.00×10−10 | 1.06×10−2 | 51.27 | 49.99 | 0.64 | 1.06×10−2 | 2.21×10−2 | 53.23 | 49.95 | 0.41 |
TC | Included | 1.41×10−107 | 5.85×10−3 | 52.03 | 49.98 | 0.32 | 5.87×10−3 | 1.49×10−2 | 51.21 | 49.97 | 0.62 |
TC | Excluded | 3.11×10−11 | 9.14×10−3 | 49.43 | 50.01 | 0.66 | 9.15×10−3 | 1.91×10−2 | 50.12 | 50.01 | 0.93 |
BMI: body mass index; HDL-C: low-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; SNP: single nucleotide polymorphism; TC: total cholesterol; TG: triglycerides; Pv: Variance (Levene’s) test P-value; Pm: marginal (linear regression) test P-value