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. Author manuscript; available in PMC: 2017 Sep 15.
Published in final edited form as: Int J Cancer. 2016 May 18;139(6):1231–1240. doi: 10.1002/ijc.30170

Figure 5. Association between lactate dehydrogenase and Epstein-Barr virus levels and overall risk of death among children with Burkitt lymphoma, Kisumu, Kenya.

Figure 5

In multivariate models adjusted for age, gender, nutritional status and tumor stage, (A) elevated serum LDH (>400 mU/ml) was associated with increased risk of death or relapse (aHR=1.84 [0.91 to 3.69]). In contrast, (B) EBV load (copies/μg DNA) was not associated with tumor stage (p=0.583) and was not found to be associated with long-term survival. Even when categorizing viral loads, (C) children with EBV viral loads of >2000 and between >200 - 2000 copies/μg DNA were 0.85 [0.34 to 2.16] and 0.95 [0.33 to 2.73] times less likely to die or suffer a relapse, respectively, as compared to children with EBV viral loads between 0 – 200 copies/μg DNA.

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