The weight of mice immunized with recombinant bacille calmette-guerins (rBCGs), including rBCG-1173:A, rBCG-1173:E, rBCG-1173:I, rBCG-1173:C, rBCG-1173:G, rBCG-1173:AE, rBCG-1173:IE, rBCG-1173:GC, rBCG-1173:GE and rBCG-1173:GCE. Mice immunized with PBST and BCG-1173 were considered to be the control groups. These mice were weighted every 2 weeks after immunization.