Table 1.
The percentages of CD4+ T splenic lymphocytes in mice immunized with recombinant bacille calmette-guerins (rBCGs).
| Groups | 6w | 8w | 10w | 12w |
|---|---|---|---|---|
| PBST | 23.40 ± 0.80 | 22.50 ± 0.71 | 23.20 ± 1.02 | 23.5 ± 0.63 |
| BCG-1173 | 30.51 ± 1.72 | 33.43 ± 0.94a | 35.74 ± 1.81b | 35.14 ± 2.32 |
| rBCG-1173:361 | 29.85 ± 2.50 | 33.65 ± 2.59a | 35.80 ± 1.19b | 34.98 ± 1.68 |
| rBCG-1173:A | 32.34 ± 3.32# | 35.77 ± 2.20a# | 36.95 ± 1.45b# | 36.55 ± 3.07# |
| rBCG-1173:E | 31.40 ± 0.23# | 34.80 ± 1.49a# | 36.90 ± 1.22b# | 36.35 ± 3.49# |
| rBCG-1173:I | 31.58 ± 1.92# | 34.45 ± 2.77a# | 36.50 ± 0.96b# | 35.87 ± 1.07# |
| rBCG-1173:C | 31.80 ± 1.93# | 34.58 ± 1.02a# | 36.18 ± 1.12b# | 35.65 ± 0.93# |
| rBCG-1173:G | 31.05 ± 2.77# | 34.61 ± 0.79a# | 36.43 ± 0.92b# | 36.63 ± 2.25# |
| rBCG-1173:AE | 35.76 ± 0.68* | 39.18 ± 1.24a* | 42.33 ± 2.34b* | 40.45 ± 1.97c* |
| rBCG-1173:IE | 35.10 ± 1.41* | 38.48 ± 1.17a* | 42.68 ± 2.50b* | 41.50 ± 1.07* |
| rBCG-1173:GC | 35.15 ± 1.10* | 37.88 ± 0.47a* | 39.15 ± 1.10b* | 38.78 ± 0.65* |
| rBCG-1173:CE | 34.83 ± 0.47* | 37.15 ± 0.45a* | 40.43 ± 1.33b* | 38.60 ± 0.98c* |
| rBCG-1173:GE | 35.36 ± 0.63* | 37.85 ± 2.25a* | 40.25 ± 1.48b* | 41.45 ± 1.48c* |
| rBCG-1173:GCE | 34.23 ± 2.50* | 38.93 ± 3.18a* | 40.58 ± 0.87b* | 42.63 ± 6.76c* |
a, b and c represent significantly differences at P < 0.05 when compared with the intervention time of 6 w, 8 w and 10 w.
*
P < 0.05 vs. BCG-1173, rBCG-1173:361, rBCG-1173:A, rBCG-1173:E, rBCG-1173:I, rBCG-1173:C and rBCG-1173:G groups.
#
P < 0.05 vs. BCG-1173 and rBCG-1173:361 groups.