Table 4.
Strains of S. pneumoniae among adults aged between 15 and 59 years.
| n (%)–[most prevalent serotype] |
||||||||
|---|---|---|---|---|---|---|---|---|
| Source | Country (year) | Study population (N) | PCV7a | PCV10-specific[1, 5, 7F] | PCV13-specific[3, 6A, 19A] | PPV23-specificb | PPV23 serotypes | NV serotypes |
| IPD | ||||||||
| Moore et al. 201524 | US (2011–13) | Adults with IPD aged between 18 and 49 y (1990) | 23 (1.2)–[4] | 62 (3.1)–[7F] | 102 (5.1)–[3] | 125 (6.3) | 22F: 4.1% • 12F: 1.9% • 8: 1.7% | 6C: 1.0% • Other NS: 79.2%c |
| 11A: 1.4% • 9N: 1.3%c | ||||||||
| Skoczynska et al. 20146 | Poland (2011–13) | Adults with IPD aged between 15 and 54 y (315) | 119 (37.8)–[4, 14] | 26 (8.3)–[1] | 71 (22.5)–[3] | 62 (19.7) | 8: 3.8% • 9N; 12F: 3.5% | 32 (10.2)–[NS] |
| 10A; 15B/C: 2.5% • 11A; 22F: 1.9% | ||||||||
| von Gottberg et al. 20149 | South Africa (2012) | Adults with IPD aged between 25 and 44 y (1260) | 256 (20.3)–[4] | 199 (15.8)–[1] | 251 (19.9)–[19A] | 320 (25.4) | 12F: 9.2% • 8: 4.7% • 9N: 3.1% | 16F: 3.1% • 13: 2.5% • 7C: 1.9% |
| 22F: 2.4% • 10A; 15B: 2.1% • 17F: 1.8% | 34: 1.3% • Other: 9.7% | |||||||
| Garcia Gabarrot et al. 20145 | Uruguay (2011–12) | Adults with IPD aged between 15 and 59 y (126) | 10 (7.9)–[NS] | 47 (37.3)–[NS]d | — | — | 69 (54.8)–[NS]e | |
| Verhaegen et al. 201457 | Belgium (2009–11) | Adults with IPD aged between 18 and 49 y (220) | 13 (5.9)–[NS] | 102 (46.4)–[1] | 22 (10.0)–[19A] | — | 12F: 7.3% • 8: 4.5% • 22F: 2.3%f | ≥ 26 (11.8)–[NS]f |
| Van Mens et al. 201464 | Netherlands (2008–10) | Adults with IPD aged between 20 and 45 y (148) | 34 (23.0)–[NS] | — | — | — | — | 114 (77.0)–[NS] |
| Wortham et al. 201459 | US (2009) | Adults with IPD aged between 18 and 49 y (978) | 536 (54.8)–[NS]g | — | — | 442 (45.2)–[NS]e | ||
| non-IPD | ||||||||
| Hammitt et al. 201430 | Kenya (2012) | NPC among adults aged 18–49 y (116) | 10 (8.6)–[NS]h | — | — | 106 (91.4)–[NS]i | ||
IPD: invasive pneumococcal disease; NA: not applicable; NS: not specified; NV: non-vaccine; SP: S. pneumoniae
a
PCV7 serotypes: 4, 6B, 9V, 14, 18C, 19F, 23F;
b
PPV23-specific serotypes: 2, 8, 9N, 10A, 11A, 12F, 15B, 17F, 20, 22F, 33F;
c
PCV serotypes and the 5 most common non-PCV serotypes were reported;
d
PCV13 serotypes not found in PCV7;
e
Non-PCV serotypes;
f
Only the serotypes accounting for at least 4% of isolates overall were reported;
g
PCV13-serotypes;
h
PCV10 serotypes;
i
Non-PCV10 serotypes.