Figure 2.

Representative histomorphology and immunophenotype of bithalamic gliomas demonstrating infiltrative growth and moderate cytologic pleomorphism. While tumors lacked immunoreactivity for H3K27M, p53 expression was mostly seen in a minority of tumor cells. The proliferative fraction, as assessed by Ki67/Mib‐1 immunolabeling, was variable from moderately to very high frequency. The scale bars represent 200 μm.