. Author manuscript; available in PMC: 2018 Dec 1.

Published in final edited form as: Int J Geriatr Psychiatry. 2016 Dec 28;32(12):e10–e17. doi: 10.1002/gps.4644

Table 2.

Cross-sectional and longitudinal effects of stress measures on WMH volume

	F value	P value
*Effects of baseline stress measures on baseline WMH volume*
Perceived stress severity	0.00	0.9772
Stressor exposure	1.24	0.2659
*Effects of baseline stress measures on change in WMH volume*
Perceived stress severity	0.18	0.6723
Stressor exposure	0.24	0.6230
*Effects of change in stress measures on change in WMH volume*
Change in perceived stress severity	2.72	0.1005
Change in stressor exposure	5.46	0.0203

Separate models examined the relationship between perceived stress severity and stressor exposure on log-transformed WMH volume. Models examining effects of cross-sectional stress measures on cross-sectional WMH volumes controlled for age, sex, race, presence of hypertension, and diagnostic cohort, with 233 degrees of freedom. Models examining effects of cross-sectional stress measures on change in WMH volumes included these same covariates along with baseline log-transformed WMH volume, with 232 degrees of freedom. Models examining the relationship between change in stress measures and change in WMH volume included those same covariates plus baseline stress measures, with 231 degrees of freedom.