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. 2017 Jun 28;7:4349. doi: 10.1038/s41598-017-04729-y

Figure 3.

Figure 3

The NF-κB signaling pathway regulates Mmm-derived LAMP-induced IL-1β expression in EBL cells. EBL cells were stimulated or not with 1 μg/ml Mmm-derived LAMPs and then treated with an NF-κB inhibitor (1,5, or 10 μM) or DMSO in the absence of serum for 6 h. The cells and supernatants were respectively harvested and analyzed by real-time PCR and ELISA. Data are presented as the mean and standard deviation of three assays. *p < 0.05 compared with LAMP-stimulated cells.