Figure 6.

Somatic (a and b) and dendritic (c and d) Paired-Pulse Facilitation (PPF) measured on hippocampal slices perfused with vehicle (artificial cerebrospinal fluid containing 0.1% ethanol), 1 µM linoleic acid (LA), 1 µM arachidonic acid (AA), 0.1 µM or 1 µM 13-hydroxyoctadecadienoic acid (13-HODE), or 0.1 µM or 1 µM prostaglandin E₂ (PGE₂). Data (mean ± SD) are expressed relative to baseline (n = 4–6 per condition). Graphs (a and c) showe the minute-by-minute data; (b and d) represent average PPF during compound incubation and washout relative to baseline (dotted line). Data were analyzed by a two-way repeated measures ANOVA followed by Dunnett’s multiple comparison test. *Significantly different compared to vehicle at a specific time point.