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. 2017 Jun 28;7:3928. doi: 10.1038/s41598-017-04283-7

Figure 3.

Figure 3

Suppression of ATP current density and P2X3 R expression after ALA treatment in diabetic rats. (A) Top: An example of ATP-evoked inward current traces recorded from NS and ALA-treatment rats. Bottom: Bar graph showed a drastical reduction in ATP-evoked current density after ALA treatment (n = 9 cells for each group, **p < 0.01, compared with NS, two-sample t-test). (B) Western blots for P2X3 Rs of T13-L2 DRGs from NS and ALA-treatment rats. Bar graph showed mean density relative to β-actin for P2X3R. ALA treatment greatly reduced expressions of P2X3Rs (n = 4 for each group, **p < 0.01, compared with NS, two-sample t-test).