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. 2017 Jun 28;7:4345. doi: 10.1038/s41598-017-04280-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Pore characteristics, in vitro swelling, and degradation of polymer/Bio-IL hydrogels. Representative SEM images of (a) GelMA/Bio-IL and (b) PEGDA/Bio-IL hydrogels formed by using 100/0 and 50/50 polymer/Bio-IL ratio at 15% (w/v) polymer concentration (1% VC, 1.5% TEOA, and 0.1 mM Eosin Y at 120 s light exposure were used to form the hydrogels). Average pore sizes of (c) GelMA/Bio-IL and (d) PEGDA/Bio-IL hydrogels at varying polymer concentrations and polymer/Bio-IL ratios. Swelling ratios of (e) GelMA/Bio-IL and (f) PEGDA/Bio-IL hydrogels at 15% final polymer concentration and 50/50 polymer/Bio-IL ratio in DPBS after 4, 8 and 24 h. Degradation of (g) GelMA/Bio-IL and (h) PEGDA/Bio-IL hydrogels at 15% final polymer concentration and 50/50 polymer/Bio-IL ratio in DPBS supplemented with 10% FBS over a two-week period. Error bars indicate standard error of the means, asterisks mark significance levels of p < 0.05 (*), p < 0.01 (**), and p < 0.001 (***).