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. 2017 Jun 28;7:4334. doi: 10.1038/s41598-017-04595-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation profile of inflammation and disease parameters in VL patients undergoing leishmanicidal therapy. (A) Heatmap shows significant correlation (p < 0.05, after adjustment for multiple measurements) of clustered Spearman matrices including serum cytokines, lipid mediators, as well as clinical, hematological, and laboratory parameters in VL patients at indicated timepoints of leishmanicidal therapy. A heatmap using the Spearman rank values was used to illustrate the matrices and only statistically significant correlations are shown. (B) A heatmap of the number of significant correlations involving each parameter examined is shown.