Table 2.
Concentrations of serum markers in the study population.
| Marker | Units | Healthy control | Visceral Leishmaniasis | P-value |
|---|---|---|---|---|
| TGF-β1 | pg/mL | 56.5 (48.4–67.9) | 21.8 (17.4–38.9) | <0.0001 |
| PGE2 | pg/mL | 0.7 (0.4–0.8) | 0.7 (0.4–1.0) | 0.669 |
| PGF2α | ng/mL | 0.4 (0.2–0.7) | 5.3 (4.0–6.5) | <0.0001 |
| LTB4 | ng/mL | 5.17 (3.6–9.3) | 16.8 (12.6–29.7) | <0.0001 |
| RvD1 | ng/mL | 82.5 (45.5–115) | 200 (92.3–369) | <0.0001 |
| TNF-α | pg/mL | 1.0 (0.6–1.9) | 21.7 (19.9–27.1) | <0.0001 |
| IL-1β | pg/mL | 0.8 (0.4–1.2) | 17.0 (14.6–22.2) | <0.0001 |
| IL-6 | pg/mL | 1.2 (0.6–2.1) | 6.5 (4.3–9.4) | <0.0001 |
| IL-8 | pg/mL | 7.0 (5.3–14.0) | 23.8 (19.2–29.8) | <0.0001 |
| IL-10 | pg/mL | 2.0 (1.5–3.2) | 58.2 (37.7–78.5) | <0.0001 |
| IL12p70 | pg/mL | 1.8 (1.5–2.3) | 8.5 (7.4–9.8) | <0.0001 |
Values represent median and interquartile ranges. Data were analyzed using the Mann-Whitney U test (continuous variables).