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. 2017 Jun 28;7:4361. doi: 10.1038/s41598-017-04709-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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DACH1 and CD44 were related to clinical outcomes of breast cancer patients. Meta-analysis of a total of 19 public databases showed that breast cancer patients with higher DACH1 mRNA level tended to have better overall survival (a), relapse-free survival (c), metastasis-free survival (e). On the contrary, patients with higher CD44 mRNA expression had shorter time to death (b) and metastasis (f), but did not acquire statistically significant worse relapse-free survival in comparison to patients with comparatively lower CD44 expression (d).