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Covalent binding of fenclozic acid-related material in organs or plasma of C57BL/6J mice 72 h after a single 10 mg/kg oral dose of [14C]-fenclozic acid
| Animal | pmol equiv/mg protein | ||
|---|---|---|---|
| Liver | Kidney | Plasma | |
| 1 | 10.70 ± 0.32 | 31.03 ± 1.20 | 7.74 ± 0.71 |
| 2 | 23.49 ± 1.58 | 48.49 ± 2.98 | 12.85 ± 1.07 |
| 3 | 18.79 ± 1.42 | 40.54 ± 3.28 | 8.09 ± 1.11 |
| Mean ± SD | 17.66 ± 6.47 | 40.02 ± 8.74 | 9.56 ± 2.85 |
Each sample is the mean ± SD of 3 determinations/animal/tissue
