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. 2017 Jun 29;8:405. doi: 10.3389/fphar.2017.00405

FIGURE 5.

FIGURE 5

Alantolactone pathway scheme. Alantolactone suppresses IL-6-stimulated TLR4 expression via STAT3 phosphorylation and SOCS3 expression, which activates AKT phosphorylation.