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Immunization decreases the parasite tissue cyst burden in infected dams. Female mice were immunized with ΔGRA17 and 70 days after they were mated and gavaged orally with 10 Pru cysts on day 12 of gestation. At 30 days after delivery, the cysts loads in brain tissue were analyzed. Non-immunized dams showed higher tissue burdens of cysts than immunized mice. Data points indicate means ± SD. Significance compared with infected mice: ***p < 0.001.
