c. between methylation status of MUC4 promoter
	hypomethylation			hypermethylation
	n	mean	±sd	n	mean	±sd	p value
Expression level of mRNA
TET1	(18)	2.21	±0.68	(42)	1.69	±0.38	0.006	**
TET2	(15)	0.43	±0.75	(41)	0.23	±0.62	0.350
TET3	(16)	2.98	±0.53	(42)	2.48	±0.78	0.008
AICDA	(18)	2.58	±0.56	(42)	2.14	±0.55	0.008
GCM1	(18)	1.93	±0.52	(42)	1.46	±0.49	0.003
Dnmt1	(16)	0.43	±0.29	(42)	−0.22	±0.53	<0.001	**
Dnmt3a	(16)	0.4	±0.24	(42)	−0.17	±0.35	<0.001

Threshold value of hypomethylation index is >2.489, **unequal T test