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. 2017 Jun 29;8:446. doi: 10.3389/fphys.2017.00446

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Copyright © 2017 Zhang, Tu, Wang, Hu, Li, Cheng, Yin, Li and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of resveratrol on BDNF expression and TrkB phosphorylation in the hippocampus induced by Pb. (A) The endogenous Bdnf transcript levels were determined by RT-qPCR from mice hippocampal homogenates of each group. Quantitative results for each sample normalized by GADPH. (B–D) Representative Western blot and quantitative results for pro- and mBDNF and phosphorylated TrkB. The densities are normalized to β-actin. Values are expressed as mean ± SEM (n = 6). ^*P < 0.05, ^***P < 0.001 compared to Cont group; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 compared to Pb group.