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. 2017 Jun 29;8:446. doi: 10.3389/fphys.2017.00446

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Copyright © 2017 Zhang, Tu, Wang, Hu, Li, Cheng, Yin, Li and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of resveratrol on SIRT1 phosphorylation in the hippocampus of Pb-exposed mice. (A) Representative Western blot and quantitative results for pSIRT1 level in the hippocampus. The densities are normalized to β-actin. (B) Representative IHF staining with pSIRT1 in CA1 region of hippocampus. (C) Correlation analysis of pSIRT1 with probe time in target quadrant in MWM test. (D) Correlation analysis of hippocampal pSIRT1 with cortical MDA level (n = 6). Values are expressed as mean ± SEM. ^**P < 0.01, ^***P < 0.001 compared to Cont group; ^##P < 0.01 compared to Pb group.