Figure 2.

ANXA4 is upregulated in human primary HCC tissues. A, B. The protein level of ANXA4 was typically upregulated (62%, 15/24) in primary HCC patient tissues (K) compared with matched noncancerous liver tissue (N). ANXA4 was downregulated in 3/24 (13%) cases, and no difference was observed in 6/24 (25%) of the HCC tissues. C. Representative images of IHC analysis of ANXA4 expression in HCC tissues, in which 58% (34/59) of the HCC tissues displayed high positive staining, 27% (16/59) showed moderate staining, and only 15% (9/59) exhibited low staining. Original magnification 40 × (left) and 200 × (right).