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Levels of crosstalk between the HIF and the NF-κB pathways. (A) NF-κB control over the HIF pathway; (B) Reported points of interaction and control of the HIF pathway over the NF-κB signalling cascade. Red T-bars indicate inhibition points, whereas arrows with dashed lines indicate regulation events that have not been proved in an in vivo system yet. Question marks are used to highlight the unanswered questions into the HIF regulation of the NF-κB pathway.
