Table 2.

FDA-approved inhibitors. These anti-angiogenesis strategies are being used in conjunction with other anticancer chemotherapeutics.

Generic Name	FDA-Approved Indication
Bevacizumab	Colorectal, non-small-cell lung, and glioblastoma multiforme
Thalidomide	Myeloma
Lenalidomide	Myeloma (myelodysplastic syndrome (MDS))
Sorafenib	Renal cell and hepatocellular carcinoma
Sunitinib	Renal cell and gastrointestinal carcinoma
Temsirolimus	Renal cell carcinoma
Axitinib	Renal cell carcinoma
Pazopanib	Renal cell carcinoma, kidney cancer, and advanced soft tissue sarcoma
Cabozantinib	Thyroid cancer
Everolimus	Kidney cancer, advanced breast cancer, pancreatic neuroendocrine tumors (PNETs), and subependymal giant cell astrocytoma
Ramucirumab	Stomach cancer and gastroesophageal junction adenocarcinoma
Regorafenib	Colorectal cancer and gastrointestinal stromal tumor
Vandetanib	Thyroid cancer
Ziv-aflibercept	Colorectal cancer